Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic Landscape of Malignant Mesotheliomas.

Molecular cancer therapeutics - 1 Oct 2016

Kato Shumei, Tomson Brett N, Buys Timon P H, Elkin Sheryl K, Carter Jennifer L, Kurzrock Razelle

Abstract excerpt

Understanding the genomic landscape of malignant mesothelioma may identify novel molecular drivers of this ultra-rare disease, which can lead to an expanded roster of targeted therapies and clinical trial options for patients with mesothelioma. We examined the molecular profiles of 42 patients with malignant mesothelioma (including pleural, peritoneal, and pericardial) that were referred by clinicians to be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Cluster Analysis
Share to Genomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lung Neoplasms

Share to Mesothelioma

Share to Mesothelioma, Malignant

Share to Molecular Targeted Therapy

Share to Neoplasm Staging

Source

Identifiers

PMID: 27507853
DOI: 10.1158/1535-7163.MCT-16-0229

Genes

BAP1
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic Landscape of Malignant Mesotheliomas.PMID 27507853Read ↗

Genomic characterization and detection of potential therapeutic targets for peritoneal mesothelioma in current practice.Semantic proximity Read ↗

Molecular Characterization of Mesothelioma: Impact of Histologic Type and Site of Origin on Molecular LandscapeSemantic proximity Read ↗

Novel Germline Mutations in DNA Damage Repair in Patients with Malignant Pleural Mesotheliomas.Semantic proximity Read ↗

Molecular alterations and potential actionable mutations in peritoneal mesothelioma: a scoping review of high-throughput sequencing studies.Semantic proximity Read ↗

Personalized Oncogenomics: Clinical Experience with Malignant Peritoneal Mesothelioma Using Whole Genome SequencingSemantic proximity Read ↗

Comprehensive genomic and transcriptomic analysis enables molecularly guided therapy options in peritoneal and pleural mesotheliomaSemantic proximity Read ↗

Genomic and transcriptomic analyses identify a prognostic gene signature and predict response to therapy in pleural and peritoneal mesotheliomaSemantic proximity Read ↗

Gender differences in molecular-guided therapy recommendations for metastatic malignant mesothelioma.Semantic proximity Read ↗

Isolated BAP1 Genomic Alteration in Malignant Pleural Mesothelioma Predicts Distinct Immunogenicity with Implications for Immunotherapeutic ResponseSemantic proximity Read ↗

Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma.Semantic proximity Read ↗

Multiple institutions’ research findings using the National Mesothelioma Virtual BankSemantic proximity Read ↗

Prevalence of incidental germline variants detected via tumor-only mesothelioma genomic profilingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.