Article

Causality of genetically determined metabolites and metabolic pathways on stroke: a two-sample mendelian randomization study

2024-07-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Stroke is the second leading cause of death worldwide. While extensive research has been conducted on stroke risk factors, the underlying biological mechanism remains not fully understood. This study aims to investigate the causal effect of circulation metabolites on stroke risk. <bold>Methods</bold> A two-sample Mendelian Randomization (MR) analysis was conducte...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0930d06c-2e21-51d3-a09f-8a7a23a9ba97
DOI: 10.21203/rs.3.rs-4641082/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Causality of genetically determined metabolites and metabolic pathways on stroke: a two-sample mendelian randomization studyDOI 10.21203/rs.3.rs-4641082/v1Read

Assessing the causal effect of genetically predicted metabolites and metabolic pathways on stroke.Semantic proximity Read

Human blood metabolites and lacunar stroke: A Mendelian randomization study.Semantic proximity Read

Causal relationship between genetically determined plasma metabolites and stroke: A two sample Mendelian randomization study.Semantic proximity Read

Mendelian Randomization in Stroke: A Powerful Approach to Causal Inference and Drug Target ValidationSemantic proximity Read

Causal relationship between human blood metabolites and risk of ischemic stroke: a Mendelian randomization studySemantic proximity Read

Potential blood biomarkers to differentiate ischemic and hemorrhagic strokesSemantic proximity Read

Genetic determinants of circulating metabolites and the risk of stroke and its subtypes.Semantic proximity Read

Causal role of lipid metabolome on the risk of ischemic stroke, its etiological subtypes, and long-term outcome: A Mendelian randomization study.Semantic proximity Read

Mendelian randomization studies on ischemic stroke: a field synopsis and systematic review.Semantic proximity Read

Causal Effect of Lipoprotein-Associated Phospholipase A2 Activity on Ischemic Stroke: A Mendelian Randomization Study.Semantic proximity Read

Exploring the causal role of fatty acids in ischemic stroke: Insights from Mendelian randomization and inflammatory mediator analysis.Semantic proximity Read

Novel Drug Targets for Ischemic Stroke Identified Through Mendelian Randomization Analysis of the Blood ProteomeSemantic proximity Read