Article
A genetic and transcriptomic assessment of the KTN1 gene in Parkinson's disease risk.
Neurobiology of aging - 1 Feb 2024
Moore Anni, Crea Peter Wild, Makarious Mary, Bandres-Ciga Sara, Blauwendraat Cornelis, Diez-Fairen Monica
Abstract excerpt
Parkinson's disease (PD) is a progressive neurological disorder caused by both genetic and environmental factors. An association has been described between KTN1 genetic variants and changes in its expression in the putamen and substantia nigra brain regions and an increased risk for PD. Here, we examine the link between PD susceptibility and KTN1 using individual-level genotyping data and summary statistics from...
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