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Article

The lifelong natural history of clonal hematopoiesis and its links to myeloid neoplasia.

Blood - 15 Feb 2024

Fabre Margarete A, Vassiliou George S

Abstract excerpt

ABSTRACT: The study of somatic mutations and the associated clonal mosaicism across the human body has transformed our understanding of aging and its links to cancer. In proliferative human tissues, stem cells compete for dominance, and those with an advantage expand clonally to outgrow their peers. In the hematopoietic system, such expansion is termed clonal hematopoiesis (CH). The forces driving competition,...

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Identifiers

PMID: 37992214
DOI: 10.1182/blood.2023019964

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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