Article
Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies.
Cell stem cell - 1 Feb 2018
Bowman Robert L, Busque Lambert, Levine Ross L
Abstract excerpt
Clonal hematopoiesis (CH) broadly describes the expansion of a clonal population of blood cells with one or more somatic mutations. Individuals with CH are at greater risk for hematological malignancies, cardiovascular disease, and increased mortality from non-hematological cancers. Understanding the causes of CH and how these mutant cells interact with cells of other tissues will provide critical insights into...
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