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Article

A Comparative Review of Methods for Detecting Epidermal Growth Factor Receptor Mutations in Cell-free DNA from Lung Cancer Patients.

Current molecular medicine - 1 Jan 2026

Shohani Sepideh, Barati Mahmood, Hosseini Arshad

Abstract excerpt

BACKGROUND: Lung cancer remains the leading cause of cancer-related mortality. Determining the T790M resistance variants and epidermal growth factor receptor (EGFR) mutations is crucial for personalized treatment, especially when using targeted therapies. OBJECTIVE: This review article aims to comprehensively compare some of the various diagnostic techniques associated with liquid biopsies, such as cell-free DNA...

Read the complete abstract on PubMed

Topics

Humans
Lung Neoplasms
ErbB Receptors
Mutation
Cell-Free Nucleic Acids
Liquid Biopsy
Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Biomarkers, Tumor

DNA Mutational Analysis

Source

Identifiers

PMID: 40635223
DOI: 10.2174/0115665240374769250703232841

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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