Article
Associations Between TREML2 Gene Variants and Alzheimer's Disease: Biomarkers, Neuroimage, and Cognition.
Journal of Alzheimer's disease : JAD - 1 Jan 2023
Li Jie-Qiong, Zhong Xiao-Ling, Song Jing-Hui, Chi Song, Xie An-Mu, Tan Lan, Yu Jin-Tai
Abstract excerpt
BACKGROUND: Recent genetic research identified a protective factor against late-onset Alzheimer's disease (AD) in Caucasians, a variant called rs3747742-C in the TREML2 gene. However, the roles of other TREML2 variants in AD have not been fully explored. OBJECTIVE: We conducted a focused analysis of 16 TREML2 variants, examining their connection to AD by studying their correlation with cerebrospinal fluid (CSF)...
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