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Article

Role of TREM2 in Alzheimer's Disease: A Long Road Ahead.

Molecular neurobiology - 1 Oct 2021

Kulkarni Bhargavi, Kumar Dileep, Cruz-Martins Natália, Sellamuthu Satheeshkumar

Abstract excerpt

Alzheimer's disease (AD) is a neurodegenerative disease characterized by an increasing deterioration of memory, which is concomitant with additional cognitive deficits. Neurofibrillary tangles and senile plaques are two pivotal proteins inside the brain that are considered essential to obstruct the normal cognitive function of the brain. Genetic variations in TREM2 gene disturb the neuroinflammatory action of...

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PMID: 34275100
DOI: 10.1007/s12035-021-02477-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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