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Article

Higher Peripheral TREM2 mRNA Levels Relate to Cognitive Deficits and Hippocampal Atrophy in Alzheimer's Disease and Amnestic Mild Cognitive Impairment.

Journal of Alzheimer's disease : JAD - 1 Jan 2017

Tan Yi Jayne, Ng Adeline S L, Vipin Ashwati, Lim Joseph K W, Chander Russell J, Ji Fang, Qiu Yingwei, Ting Simon K S, Hameed Shahul, Lee Tih-Shih, Zeng Li, Kandiah Nagaendran, Zhou Juan

Abstract excerpt

BACKGROUND: Variants in triggering receptor expressed on myeloid cells 2 (TREM2) are associated with increased Alzheimer's disease (AD) risk. Recent studies have reported inconsistent peripheral TREM2 mRNA expression levels and relationship with cognitive scores in AD and mild cognitive impairment (MCI). Additionally, no study has examined the association of peripheral TREM2 levels with neuroimaging measures in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28453482
DOI: 10.3233/JAD-161277

Genes

TREM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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