Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

H2S Regulates the Phenotypic Transformation of Astrocytes Following Cerebral Ischemia/Reperfusion via Inhibiting the RhoA/ROCK Pathway.

Molecular neurobiology - 1 Jun 2024

Ding Yanyu, Fang Fang, Liu Xiaolong, Sheng Shuyan, Li Xueyan, Yin Xiaojiao, Chen Zhiwu, Wen Jiyue

Abstract excerpt

The role of hydrogen sulfide (H2S) on the phenotypic change of astrocytes following cerebral ischemia/reperfusion (I/R) in mice was investigated in present study. We tested the expression of glial fibrillary acidic protein (GFAP), A2 phenotype marker S100a10, and A1 phenotype marker C3 protein and assessed the change of BrdU/GFAP-positive cells, GFAP/C3-positive cells, and GFAP/S100a10-positive cells in mice...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytes
Share to Brain Ischemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Proliferation

Share to Hydrogen Sulfide

Share to Mice, Knockout

Share to Reperfusion Injury

Share to rho-Associated Kinases

Share to rhoA GTP-Binding Protein

Source

Identifiers

PMID: 37978158
DOI: 10.1007/s12035-023-03797-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

H2S Regulates the Phenotypic Transformation of Astrocytes Following Cerebral Ischemia/Reperfusion via Inhibiting the RhoA/ROCK Pathway.PMID 37978158Read ↗

Downregulation of cystathionine β-synthase/hydrogen sulfide contributes to rotenone-induced microglia polarization toward M1 type.Semantic proximity Read ↗

Recent Advances in the Role of Hydrogen Sulfide in Ischemia-Reperfusion InjurySemantic proximity Read ↗

Hydrogen Sulfide Contributes to Retinal Neovascularization in Ischemia-Induced RetinopathySemantic proximity Read ↗

Astrocyte phenotype and prevention against oxidative damage in neurotoxicity.Semantic proximity Read ↗

High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress.Semantic proximity Read ↗

Remazolam affects the phenotype and function of astrocytes to improve traumatic brain injury by regulating the Cx43.Semantic proximity Read ↗

Effects of therapeutic hypothermia on the glial proteome and phenotype.Semantic proximity Read ↗

Hydrogen Sulfide as a Potential Therapeutic Target in FibrosisSemantic proximity Read ↗

Rho Kinase Inhibitor Y27632 Improves Recovery After Spinal Cord Injury by Shifting Astrocyte Phenotype and Morphology via the ROCK/NF-κB/C3 Pathway.Semantic proximity Read ↗

Regulation of cystathionine gamma-lyase/H₂S system and its pathological implication.Semantic proximity Read ↗

HSF1 is involved in suppressing A1 phenotype conversion of astrocytes following spinal cord injury in rats.Semantic proximity Read ↗

Phenotypic assays to identify agents that induce reactive gliosis: a counter-screen to prioritize compounds for preclinical animal studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.