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Article

Hydrogen Sulfide Contributes to Retinal Neovascularization in Ischemia-Induced Retinopathy

7 Jun 2016

Abstract excerpt

PURPOSE: Hydrogen sulfide (H2S) is an endogenous gaseous signaling molecule with significant pathophysiological importance, but its role in retinal neovascular diseases is unknown. Hydrogen sulfide is generated from L-cysteine by cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE), and/or 3-mercaptopyruvate sulfurtransferase (3-MST). The aim of this study was to investigate the role of H2S in retinal...

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PMID: 27273718
DOI: 10.1167/iovs.15-18555

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