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Neuroblastoma Patients’ Outcome and Chromosomal Instability

24 Oct 2023

Abstract excerpt

Chromosomal instability (CIN) induces a high rate of losses or gains of whole chromosomes or parts of chromosomes. It is a hallmark of most human cancers and one of the causes of aneuploidy and intra-tumor heterogeneity. The present study aimed to evaluate the potential prognostic role of CIN in NB patients at diagnosis. We performed array comparative genomic hybridization analyses on 451 primary NB patients at...

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PMID: 37958497
DOI: 10.3390/ijms242115514

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