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Article

Chromosomal CGH identifies patients with a higher risk of relapse in neuroblastoma without MYCN amplification

19 Jun 2007

Abstract excerpt

Whereas neuroblastoma (NB) with MYCN amplification presents a poor prognosis, no single marker allows to reliably predict outcome in tumours without MYCN amplification. We report here an extensive analysis of 147 NB samples at diagnosis, without MYCN amplification, by chromosomal comparative genomic hybridisation (CGH), providing a comprehensive overview of their genomic imbalances. Comparative genomic...

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PMID: 17579628
DOI: 10.1038/sj.bjc.6603820

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