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Article

Neuroblastomas have distinct genomic DNA profiles that predict clinical phenotype and regional gene expression.

Genes, chromosomes & cancer - 1 Oct 2007

Mosse Yael P, Diskin Sharon J, Wasserman Nora, Rinaldi Katherine, Attiyeh Edward F, Cole Kristina, Jagannathan Jayanti, Bhambhani Karishma, Winter Cynthia, Maris John M

Abstract excerpt

Neuroblastoma is a heterogeneous neoplasm that has served as a paradigm for the clinical utility of somatically acquired genomic aberrations. DNA copy number alterations (CNA) are currently used to predict prognosis, including MYCN amplification and deletions at chromosome bands 1p36 and 11q23. We predicted that genome-wide assessment of DNA aberrations in neuroblastoma tumors would provide a more precise...

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PMID: 17647283
DOI: 10.1002/gcc.20477

Genes

MYCN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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