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Article

Accumulation of Segmental Alterations Determines Progression in Neuroblastoma

2 Jun 2010

Abstract excerpt

PURPOSE: Neuroblastoma is characterized by two distinct types of genetic profiles, consisting of either numerical or segmental chromosome alterations. The latter are associated with a higher risk of relapse, even when occurring together with numerical alterations. We explored the role of segmental alterations in tumor progression and the possibility of evolution from indolent to aggressive genomic types. PATIENTS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20516441
DOI: 10.1200/jco.2009.26.7955

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