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Article

Wide reference databases for typing Trypanosoma cruzi based on amplicon sequencing of the minicircle hypervariable region.

PLoS neglected tropical diseases - 1 Nov 2023

Rusman Fanny, Díaz Anahí G, Ponce Tatiana, Floridia-Yapur Noelia, Barnabé Christian, Diosque Patricio, Tomasini Nicolás

Abstract excerpt

BACKGROUND: Trypanosoma cruzi, the etiological agent of Chagas Disease, exhibits remarkable genetic diversity and is classified into different Discrete Typing Units (DTUs). Strain typing techniques are crucial for studying T. cruzi, because their DTUs have significant biological differences from one another. However, there is currently no methodological strategy for the direct typing of biological materials that...

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Identifiers

PMID: 37956210
DOI: 10.1371/journal.pntd.0011764
PMCID: PMC10681310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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