Genomic diversity of Trypanosoma cruzi clinical isolates: a retrospective analysis

Abstract excerpt

Background Trypanosoma cruzi causes Chagas disease, a poorly understood and clinically heterogeneous disease. Recent work has shown that parasites adapted to laboratory conditions exhibit genomic variation; however, little is known of the extent of genomic diversity among clinically isolated specimens. In this study, we aimed to describe genomic diversity within a set of clinically isolated strains. Methods We...

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