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Repertoire, genealogy and genomic organization of cruzipain and homologous genes in Trypanosoma cruzi, T. cruzi-like and other trypanosome species.

PloS one - 1 Jan 2012

Lima Luciana, Ortiz Paola A, da Silva Flávia Maia, Alves João Marcelo P, Serrano Myrna G, Cortez Alane P, Alfieri Silvia C, Buck Gregory A, Teixeira Marta M G

Abstract excerpt

Trypanosoma cruzi, the agent of Chagas disease, is a complex of genetically diverse isolates highly phylogenetically related to T. cruzi-like species, Trypanosoma cruzi marinkellei and Trypanosoma dionisii, all sharing morphology of blood and culture forms and development within cells. However, they differ in hosts, vectors and pathogenicity: T. cruzi is a human pathogen infective to virtually all mammals whilst...

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PMID: 22685565
DOI: 10.1371/journal.pone.0038385
PMCID: PMC3369871

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