Article
Exploring Trypanosoma cruzi transmission dynamics in an acute Chagas disease outbreak using next-generation sequencing.
Parasites & vectors - 18 Sept 2024
Cruz-Saavedra Lissa, Ospina Carlos, Gutiérrez Stivenn A, Jaimes-Dueñez Jeiczon, Cantillo-Barraza Omar, Hernández Carolina, Álvarez Francisco, Blanco María, Leal Bernardo, Martínez Lida, Medina Manuel, Medina Mabel, Valdivieso Silvia, Ramirez Celis Lauren Natalia, Patiño Luz H, Ramírez Juan David
Abstract excerpt
BACKGROUND: Chagas disease (CD), caused by Trypanosoma cruzi, poses a major global public health challenge. Although vector-borne transmission is the primary mode of infection, oral transmission is increasingly concerning. METHODS: This study utilized long-amplicon-based sequencing (long-ABS), focusing on the 18S rRNA gene, to explore T. cruzi's genetic diversity and transmission dynamics during an acute CD...
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