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Article

Inhibitory effects of beta-carotene on preneoplastic lesions induced in Wistar rats by the resistant hepatocyte model.

Carcinogenesis - 1 Oct 1991

Moreno F S, Rizzi M B, Dagli M L, Penteado M V

Abstract excerpt

The inhibitory effects of beta-carotene (BC) on preneoplastic lesions induced in male Wistar rats by the resistant hepatocyte model was investigated. Rats were divided into six groups. Initiation was performed in all animals by a single injection of diethylnitrosamine. During the selection/promotion period five doses of 2-acetylaminofluorene were administered to the rats and a partial hepatectomy was performed....

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PMID: 1934263
DOI: 10.1093/carcin/12.10.1817

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