Article
Delineation of antigenic pathways of ethionine-induced liver cancer in the rat.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 1996
Hixson D C, Affigne S, Faris R A, McBride A C
Abstract excerpt
Although oval cell proliferation is observed prior to the appearance of hepatic nodules and hepatocellular carcinomas during ethionine-induced liver carcinogenesis in the rat, the role of these presumptive hepatic stem cells during the neoplastic process remains controversial. In order to investigate this question, we have used a panel of monoclonal antibodies against antigens associated with normal hepatocytes,...
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