Article

ezQTL: A Web Platform for Interactive Visualization and Colocalization of Quantitative Trait Loci and GWAS

2022-03-09

Abstract excerpt

Genome-wide association studies (GWASs) have identified thousands of genomic loci associated with complex diseases and traits, including cancer. The vast majority of common trait-associated variants identified via GWAS fall in non-coding regions of the genome, posing a challenge in elucidating the causal variants, genes, and mechanisms involved. Expression quantitative trait locus (eQTL) and other molecular QTL st...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 989edb15-21d5-5ec4-93c6-4831298bc88a
DOI: 10.1101/2022.03.08.483491

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ezQTL: A Web Platform for Interactive Visualization and Colocalization of Quantitative Trait Loci and GWASDOI 10.1101/2022.03.08.483491Read

ezQTL: A Web Platform for Interactive Visualization and Colocalization of QTLs and GWAS Loci.Semantic proximity Read

COLSTATS: an interactive web platform for systematic colocalization of GWAS and QTL summary statisticsSemantic proximity Read

ColocQuiaL: a QTL-GWAS colocalization pipeline.Semantic proximity Read

xQTLbiolinks: a comprehensive and scalable tool for integrative analysis of molecular QTLsSemantic proximity Read

COLOCdb: a comprehensive resource for multi-model colocalization of complex traits.Semantic proximity Read

RACER: A data visualization strategy for exploring multiple genetic associationsSemantic proximity Read

xQTLbiolinks: a comprehensive and scalable tool for integrative analysis of molecular QTLs.Semantic proximity Read

Identification of putative effector genes across the GWAS Catalog using molecular quantitative trait loci from 68 tissues and cell typesSemantic proximity Read

A powerful and versatile colocalization test.Semantic proximity Read

A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits.Semantic proximity Read

Ultra-fast genetic colocalisation across millions of association signals.Semantic proximity Read

Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics.Semantic proximity Read