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Article

ezQTL: A Web Platform for Interactive Visualization and Colocalization of QTLs and GWAS Loci.

Genomics, proteomics & bioinformatics - 1 Jun 2022

Zhang Tongwu, Klein Alyssa, Sang Jian, Choi Jiyeon, Brown Kevin M

Abstract excerpt

Genome-wide association studies (GWAS) have identified thousands of genomic loci associated with complex diseases and traits, including cancer. The vast majority of common trait-associated variants identified via GWAS fall in non-coding regions of the genome, posing a challenge in elucidating the causal variants, genes, and mechanisms involved. Expression quantitative trait locus (eQTL) and other molecular QTL...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35643189
DOI: 10.1016/j.gpb.2022.05.004
PMCID: PMC9801033

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