Establishment of a tissue‐engineered colon cancer model for comparative analysis of cancer cell lines

Abstract excerpt

Abstract To overcome the limitations of in vitro two‐dimensional (2D) cancer models in mimicking the complexities of the native tumor milieu, three‐dimensional (3D) engineered cancer models using biomimetic materials have been introduced to more closely recapitulate the key attributes of the tumor microenvironment. Specifically, for colorectal cancer (CRC), a few studies have developed 3D engineered tumor models...

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