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Spheroids and organoids derived from colorectal cancer as tools for in vitro drug screening

25 Apr 2024

Abstract excerpt

Colorectal cancer (CRC) is a heterogeneous disease. Conventional two-dimensional (2D) culture employing cell lines was developed to study the molecular properties of CRC in vitro. Although these cell lines which are isolated from the tumor niche in which cancer develop, the translation to human model such as studying drug response is often hindered by the inability of cell lines to recapture original tumor...

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PMID: 38745769
DOI: 10.37349/etat.2024.00226

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