Article

Comparative Study of Colorectal Cancer Cell Lines Cultured in Two- and Three- Dimensional Models: Insights into Cellular Morphologies, Drug Responsiveness and Transcriptomics

2023-05-17

Abstract excerpt

Drug development is a time-consuming and expensive process, given the low success rate of clinical trials. Now, anticancer drug developments have shifted to three-dimensional (3D) models which are more likely to mimic tumor behavior compared to traditional two-dimensional (2D) cultures. A comparative study among different aspects was conducted between 2D and 3D cultures using colorectal cancer (CRC) cell lines, in...

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Literature Corpus work: 2ce1b38e-4618-5060-9a8f-b1acb975bf08
DOI: 10.21203/rs.3.rs-2899480/v1

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