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Article

Unraveling Haplotype Diversity of the Apical Membrane Antigen-1 Gene in Plasmodium falciparum Populations in Thailand.

The Korean journal of parasitology - 1 Apr 2018

Lumkul Lalita, Sawaswong Vorthon, Simpalipan Phumin, Kaewthamasorn Morakot, Harnyuttanakorn Pongchai, Pattaradilokrat Sittiporn

Abstract excerpt

Development of an effective vaccine is critically needed for the prevention of malaria. One of the key antigens for malaria vaccines is the apical membrane antigen 1 (AMA-1) of the human malaria parasite Plasmodium falciparum, the surface protein for erythrocyte invasion of the parasite. The gene encoding AMA-1 has been sequenced from populations of P. falciparum worldwide, but the haplotype diversity of the gene...

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Identifiers

PMID: 29742870
DOI: 10.3347/kjp.2018.56.2.153
PMCID: PMC5976018

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