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Article

Sequence diversity and natural selection at domain I of the apical membrane antigen 1 among Indian Plasmodium falciparum populations.

Malaria journal - 22 Nov 2007

Garg Sheena, Alam Mohammad T, Das Manoj K, Dev Vas, Kumar Ashwani, Dash Aditya P, Sharma Yagya D

Abstract excerpt

BACKGROUND: The Plasmodium falciparum apical membrane antigen 1 (AMA1) is a leading malaria vaccine candidate antigen. The complete AMA1 protein is comprised of three domains where domain I exhibits high sequence polymorphism and is thus named as the hyper-variable region (HVR). The present study describes the extent of genetic polymorphism and natural selection at domain I of the ama1 gene among Indian P....

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Identifiers

PMID: 18031585
DOI: 10.1186/1475-2875-6-154
PMCID: PMC2211494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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