Article
Genetic structure of apical membrane antigen-1 in Plasmodium falciparum isolates from Pakistan.
Parasites, hosts and diseases - 1 Aug 2024
Zaib Komal, Khan Asifullah, Khan Muhammad Umair, Ullah Ibrar, Võ Tuấn Cường, Kang Jung-Mi, Lê Hương Giang, Na Byoung-Kuk, Afridi Sahib Gul
Abstract excerpt
Plasmodium falciparum apical membrane antigen-1 (PfAMA-1) is a major candidate for the blood-stage malaria vaccine. Genetic polymorphisms of global pfama-1suggest that the genetic diversity of the gene can disturb effective vaccine development targeting this antigen. This study was conducted to explore the genetic diversity and gene structure of pfama-1 among P. falciparum isolates collected in the Khyber...
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