Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regenerating human skeletal muscle forms an emerging niche in vivo to support PAX7 cells

2 Nov 2023

Abstract excerpt

Abstract Skeletal muscle stem and progenitor cells including those derived from human pluripotent stem cells (hPSCs) offer an avenue towards personalized therapies and readily fuse to form human–mouse myofibres in vivo. However, skeletal muscle progenitor cells (SMPCs) inefficiently colonize chimeric stem cell niches and instead associate with human myofibres resembling foetal niches. We hypothesized competition...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Muscle Physiology and Disorders
Share to Pluripotent Stem Cells Research
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37919520
DOI: 10.1038/s41556-023-01271-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regenerating human skeletal muscle forms an emerging niche in vivo to support PAX7 cellsPMID 37919520Read ↗

Differentiation of the human PAX7-positive myogenic precursors/satellite cell lineage in vitroSemantic proximity Read ↗

Human satellite cells have regenerative capacity and are genetically manipulableSemantic proximity Read ↗

Human Satellite Cell Transplantation and Regeneration from Diverse Skeletal MusclesSemantic proximity Read ↗

Human myogenic reserve cells are quiescent stem cells that contribute to muscle regeneration after intramuscular transplantation in immunodeficient miceSemantic proximity Read ↗

Functionally heterogeneous human satellite cells identified by single cell RNA sequencingSemantic proximity Read ↗

Are Human and Mouse Satellite Cells Really the Same?Semantic proximity Read ↗

Human and Mouse Skeletal Muscle Stem Cells: Convergent and Divergent Mechanisms of MyogenesisSemantic proximity Read ↗

Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7.Semantic proximity Read ↗

Generation of Skeletal Muscle Organoids from Human Pluripotent Stem CellsSemantic proximity Read ↗

Engineering human pluripotent stem cells into a functional skeletal muscle tissueSemantic proximity Read ↗

Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitorsSemantic proximity Read ↗

Skeletal Muscle Satellite Cells Co-Opt the Tenogenic Gene <i>Scleraxis</i> to Instruct RegenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.