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Article

Differentiation of the human PAX7-positive myogenic precursors/satellite cell lineage in vitro

1 Jan 2020

Abstract excerpt

Satellite cells (SC) are muscle stem cells which can regenerate adult muscles upon injury. Most SC originate from PAX7-positive myogenic precursors set aside during development. While myogenesis has been studied in mouse and chicken embryos, little is known about human muscle development. Here, we report the generation of human induced Pluripotent Stem (iPS) cell reporter lines in which fluorescent proteins have...

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PMID: 32541004
DOI: 10.1242/dev.187344

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