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Article

Functionally heterogeneous human satellite cells identified by single cell RNA sequencing

1 Apr 2020

Abstract excerpt

Although heterogeneity is recognized within the murine satellite cell pool, a comprehensive understanding of distinct subpopulations and their functional relevance in human satellite cells is lacking. We used a combination of single cell RNA sequencing and flow cytometry to identify, distinguish, and physically separate novel subpopulations of human PAX7+ satellite cells (Hu-MuSCs) from normal muscles. We found...

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PMID: 32234209
DOI: 10.7554/elife.51576

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