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NRF2 signaling pathway and telomere length in aging and age-related diseases

2 Nov 2023

Abstract excerpt

The transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) is well recognized as a critical regulator of redox, metabolic, and protein homeostasis, as well as the regulation of inflammation. An age-associated decline in NRF2 activity may allow oxidative stress to remain unmitigated and affect key features associated with the aging phenotype, including telomere shortening. Telomeres, the...

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Share to Circadian rhythm and melatonin
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PMID: 37917279
DOI: 10.1007/s11010-023-04878-x

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