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Article

Genetic Markers Regulating Blood Pressure in Extreme Discordant Sib Pairs.

Genes - 25 Sept 2023

Yasmin, O'Shaughnessy Kevin M

Abstract excerpt

Genome-wide scans performed in affected sib pairs have revealed small and often inconsistent clues to the loci responsible for the inherited components of hypertension. Since blood pressure is a quantitative trait regulated by many loci, two siblings at opposite extremes of the blood pressure distribution are more likely to have inherited different alleles at any given locus. Hence, we investigated an extreme...

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PMID: 37895212
DOI: 10.3390/genes14101862
PMCID: PMC10606487

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