Article
Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings.
Circulation - 23 Mar 1999
Krushkal J, Ferrell R, Mockrin S C, Turner S T, Sing C F, Boerwinkle E
Abstract excerpt
BACKGROUND: Elevated blood pressure is a risk factor for cardiovascular, cerebrovascular, and renal diseases. Complex mechanisms of blood pressure regulation pose a challenge to identifying genetic factors that influence interindividual blood pressure variation in the population at large. METHODS AND RESULTS: We performed a genome-wide linkage analysis of systolic blood pressure in humans using an efficient,...
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