Article
Genome-wide scan for blood pressure in Australian and Dutch subjects suggests linkage at 5P, 14Q, and 17P.
Hypertension (Dallas, Tex. : 1979) - 1 Apr 2007
Hottenga Jouke-Jan, Whitfield John B, Posthuma Danielle, Willemsen Gonneke, de Geus Eco J C, Martin Nicholas G, Boomsma Dorret I
Abstract excerpt
Large-scale studies estimate the heritability of blood pressure at approximately 50%. We carried out a genome-wide linkage analysis to search for chromosomal loci that might explain this heritability using longitudinal, multiple measures of systolic and diastolic blood pressure obtained in sibling pairs and dizygotic twin pairs from 2 countries (a total of 286 pairs from Australia and 636 pairs from the...
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