Article
AGIDB: a versatile database for genotype imputation and variant decoding across species.
Nucleic acids research - 5 Jan 2024
Zhang Kaili, Liang Jiete, Fu Yuhua, Chu Jinyu, Fu Liangliang, Wang Yongfei, Li Wangjiao, Zhou You, Li Jinhua, Yin Xiaoxiao, Wang Haiyan, Liu Xiaolei, Mou Chunyan, Wang Chonglong, Wang Heng, Dong Xinxing, Yan Dawei, Yu Mei, Zhao Shuhong, Li Xinyun, Ma Yunlong
Abstract excerpt
The high cost of large-scale, high-coverage whole-genome sequencing has limited its application in genomics and genetics research. The common approach has been to impute whole-genome sequence variants obtained from a few individuals for a larger population of interest individually genotyped using SNP chip. An alternative involves low-coverage whole-genome sequencing (lcWGS) of all individuals in the larger...
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