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Article

A cross-ancestry genome-wide meta-analysis, fine-mapping, and gene prioritization approach to characterize the genetic architecture of adiponectin.

HGG advances - 11 Jan 2024

Sarsani Vishal, Brotman Sarah M, Xianyong Yin, Fernandes Silva Lillian, Laakso Markku, Spracklen Cassandra N

Abstract excerpt

Previous genome-wide association studies (GWASs) for adiponectin, a complex trait linked to type 2 diabetes and obesity, identified >20 associated loci. However, most loci were identified in populations of European ancestry, and many of the target genes underlying the associations remain unknown. We conducted a cross-ancestry adiponectin GWAS meta-analysis in ≤46,434 individuals from the Metabolic Syndrome in Men...

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Share to Adiponectin
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37859345
DOI: 10.1016/j.xhgg.2023.100252
PMCID: PMC10652123

Genes

ADIPOQ
CDH13
CSF1
HCAR1
RGS17
ZNF664

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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