Article
A meta-analysis and polygenic score study identifies novel genetic markers for waist-hip ratio in African populations.
Obesity (Silver Spring, Md.) - 1 Nov 2024
Zhong Michael, Onyenobi Ebuka, Duomatey Ayo, Chen Guanjie, Perry James, Ye Zhenyao, Rotimi Charles, Adebamowo Clement A, Adeyemo Adebowale, Adebamowo Sally N
Abstract excerpt
OBJECTIVE: Understanding the genetic underpinnings of anthropometric traits in diverse populations is crucial for gaining insights into their biological mechanisms and potential implications for health. METHODS: We conducted a genome-wide association study, meta-analysis, and gene set analysis of waist-hip ratio (WHR), WHR adjusted for BMI (WHRadjBMI), waist circumference, BMI, and height using the African...
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