Macrophage phenotype transitions in a stochastic gene-regulatory network model.

Abstract excerpt

Polarization is the process by which a macrophage cell commits to a phenotype based on external signal stimulation. To know how this process is affected by random fluctuations and events within a cell is of utmost importance to better understand the underlying dynamics and predict possible phenotype transitions. For this purpose, we develop a stochastic modeling approach for the macrophage polarization process....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gene Regulatory Networks
• Share to Phenotype
• Share to Probability