Article

Bistability in macrophage polarization and metabolic implications

2021-12-25

Abstract excerpt

Macrophages are essential innate immune cells characterized by a high diversity and plasticity. In vitro, their full dynamic range of activation profiles include the classical pro-inflammatory (M1) and the alternative anti-inflammatory (M2) program. Bistability usually arises in biological systems that contain a positive-feedback loop or a mutually inhibitory, double-negative-feedback loop, which are common regula...

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Literature Corpus work: 64fac34e-6f00-5887-8ee9-f6040b773532
DOI: 10.20944/preprints202112.0416.v1

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