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Article

Depressive symptoms and hippocampal volume in autosomal dominant Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Feb 2024

Langella Stephanie, Lopera Francisco, Baena Ana, Fox-Fuller Joshua T, Munera Diana, Martinez Jairo E, Giudicessi Averi, Vannini Patrizia, Hanseeuw Bernard J, Marshall Gad A, Quiroz Yakeel T, Gatchel Jennifer R

Abstract excerpt

INTRODUCTION: Depressive symptoms are among early behavioral changes in Alzheimer's disease (AD); however, the relationship between neurodegeneration and depressive symptoms remains inconclusive. To better understand this relationship in preclinical AD, we examined hippocampal volume and depressive symptoms in cognitively unimpaired carriers of the presenilin-1 (PSEN1) E280A mutation for autosomal dominant AD....

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Identifiers

PMID: 37837524
DOI: 10.1002/alz.13501
PMCID: PMC10916972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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