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Article

Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network.

Brain : a journal of neurology - 1 Apr 2015

Ringman John M, Liang Li-Jung, Zhou Yan, Vangala Sitaram, Teng Edmond, Kremen Sarah, Wharton David, Goate Alison, Marcus Daniel S, Farlow Martin, Ghetti Bernardino, McDade Eric, Masters Colin L, Mayeux Richard P, Rossor Martin, Salloway Stephen, Schofield Peter R, Cummings Jeffrey L, Buckles Virginia, Bateman Randall, Morris John C

Abstract excerpt

Prior studies indicate psychiatric symptoms such as depression, apathy and anxiety are risk factors for or prodromal symptoms of incipient Alzheimer's disease. The study of persons at 50% risk for inheriting autosomal dominant Alzheimer's disease mutations allows characterization of these symptoms before progressive decline in a population destined to develop illness. We sought to characterize early behavioural...

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Identifiers

PMID: 25688083
DOI: 10.1093/brain/awv004
PMCID: PMC4963801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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