Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regionally specific changes in the hippocampal circuitry accompany progression of cerebrospinal fluid biomarkers in preclinical Alzheimer's disease.

Human brain mapping - 1 Feb 2018

Tardif Christine L, Devenyi Gabriel A, Amaral Robert S C, Pelleieux Sandra, Poirier Judes, Rosa-Neto Pedro, Breitner John, Chakravarty M Mallar

Abstract excerpt

Neuropathological and in vivo brain imaging studies agree that the cornu ammonis 1 and subiculum subfields of the hippocampus are most vulnerable to atrophy in the prodromal phases of Alzheimer's disease (AD). However, there has been limited investigation of the structural integrity of the components of the hippocampal circuit, including subfields and extra-hippocampal white matter structure, in relation to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid beta-Peptides
Share to Apolipoprotein E4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hippocampus

Share to Magnetic Resonance Imaging

Share to Neural Pathways

Share to Prodromal Symptoms

Share to tau Proteins

Share to White Matter

Source

Open in PubMed Open full text

Identifiers

PMID: 29164798
DOI: 10.1002/hbm.23897
PMCID: PMC6866392

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regionally specific changes in the hippocampal circuitry accompany progression of cerebrospinal fluid biomarkers in preclinical Alzheimer's disease.PMID 29164798Read ↗

Hippocampal Subregions are Differentially Affected in the Progression to Alzheimer's DiseaseSemantic proximity Read ↗

Associations between Alzheimer’s disease polygenic risk scores and hippocampal subfield volumes in 17,161 UK Biobank participantsSemantic proximity Read ↗

Associations between Alzheimer’s disease polygenic risk scores and hippocampal subfield volumes in 17,161 UK Biobank participantsSemantic proximity Read ↗

Differences in hippocampal subfield volume are seen in phenotypic variants of early onset Alzheimer's diseaseSemantic proximity Read ↗

The human hippocampus and its subfield volume across age, sex and APOE e4 statusSemantic proximity Read ↗

Spatial proteomics of hippocampal subfield‐specific pathology in Alzheimer's disease and primary age‐related tauopathySemantic proximity Read ↗

Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia.Semantic proximity Read ↗

MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers.Semantic proximity Read ↗

Low plasma ApoE levels are associated with smaller hippocampal size in the Alzheimer's disease neuroimaging initiative cohort.Semantic proximity Read ↗

Using diffusion MRI to relate hippocampal subfield microstructure to delayed verbal memory in cognitively intact individuals at genetic risk for developing Alzheimer's disease.Semantic proximity Read ↗

Using diffusion MRI to relate hippocampal subfield microstructure to delayed verbal memory in cognitively intact individuals at genetic risk for developing Alzheimer’s diseaseSemantic proximity Read ↗

Executive function changes before memory in preclinical Alzheimer's pathology: a prospective, cross-sectional, case control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.