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Article

Newly discovered genomic mutation patterns in radiation-induced small intestinal tumors of ApcMin/+ mice.

PloS one - 1 Jan 2023

Iizuka Daisuke, Sasatani Megumi, Ishikawa Atsuko, Daino Kazuhiro, Hirouchi Tokuhisa, Kamiya Kenji

Abstract excerpt

Among the small intestinal tumors that occur in irradiated mice of the established mouse model B6/B6-Chr18MSM-F1 ApcMin/+, loss of heterozygosity analysis can be utilized to estimate whether a deletion in the wild-type allele containing the Adenomatous polyposis coli (Apc) region (hereafter referred to as Deletion), a duplication in the mutant allele with a nonsense mutation at codon 850 of Apc (Duplication), or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37824459
DOI: 10.1371/journal.pone.0292643
PMCID: PMC10569626

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Newly discovered genomic mutation patterns in radiation-induced small intestinal tumors of ApcMin/+ mice.PMID 37824459Read ↗

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