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Article

Intestinal and extra-intestinal tumor multiplicities in the Apc1638N mouse model after exposure to X-rays.

Carcinogenesis - 1 Nov 1997

van der Houven van Oordt C W, Smits R, Williamson S L, Luz A, Khan P M, Fodde R, van der Eb A J, Breuer M L

Abstract excerpt

Seven-week-old Apc1638N mice were exposed to a single dose of 5 Gy total-body X-irradiation resulting in a 8-fold increase in the number of intestinal tumors and a reduction of the lifespan to an average of 6 months. The distribution of tumors along the intestinal tract as well as the adenoma/carcinoma ratio, were similar between non-irradiated and irradiated animals. Semi-quantitative PCR analysis of...

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Source

Identifiers

PMID: 9395221
DOI: 10.1093/carcin/18.11.2197

Genes

APC
FAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Intestinal and extra-intestinal tumor multiplicities in the Apc1638N mouse model after exposure to X-rays.PMID 9395221Read ↗

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