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Article

Direct single gene mutational events account for radiation-induced intestinal adenoma yields in Apc(Min/+) mice.

Radiation research - 1 May 2005

Ellender Michele, Harrison John D, Edwards Alan A, Bouffler Simon D, Cox Roger

Abstract excerpt

Data on the induction of small intestinal tumors, predominantly adenomas, by X radiation in Apc(Min/+) mice are reported. Comparison of these incidences with estimates of radiation-induced direct single gene mutation frequencies taken from the literature support the hypothesis that direct mutational loss of Apc+ is the sole requirement for initiation of adenoma. Furthermore, estimates of radiation-induced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15850417
DOI: 10.1667/rr3335

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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