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Article

Sex-dependent differences in intestinal tumorigenesis induced in Apc1638N/+ mice by exposure to γ rays.

International journal of radiation oncology, biology, physics - 1 Jan 2013

Trani Daniela, Moon Bo-Hyun, Kallakury Bhaskar, Hartmann Dan P, Datta Kamal, Fornace Albert J

Abstract excerpt

PURPOSE: The purpose of the present study was to assess the effect of 1 and 5 Gy radiation doses and to investigate the interplay of gender and radiation with regard to intestinal tumorigenesis in an adenomatous polyposis coli (APC) mutant mouse model. METHODS AND MATERIALS: Apc1638N/+ female and male mice were exposed whole body to either 1 Gy or 5 Gy of γ rays and euthanized when most of the treated mice became...

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Source

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Identifiers

PMID: 22503525
DOI: 10.1016/j.ijrobp.2012.02.053
PMCID: PMC3689297

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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