Article
Herpes Simplex Virus 1 Counteracts Tetherin Restriction via Its Virion Host Shutoff Activity
25 Sept 2013
Abstract excerpt
The interferon-inducible membrane protein tetherin (Bst-2, or CD317) is an antiviral factor that inhibits enveloped virus release by cross-linking newly formed virus particles to the producing cell. The majority of viruses that are sensitive to tetherin restriction appear to be those that acquire their envelopes at the plasma membrane, although many viruses, including herpesviruses, envelope at intracellular...
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