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The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells

7 Dec 2017

Abstract excerpt

Vesicular stomatitis virus (VSV) release from infected cells is inhibited by the interferon (IFN)-inducible antiviral host cell factor tetherin (BST-2, CD317). However, several viruses encode tetherin antagonists and it is at present unknown whether residual VSV spread in tetherin-positive cells is also promoted by a virus-encoded tetherin antagonist. Here, we show that the viral glycoprotein (VSV-G) antagonizes...

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PMID: 29216247
DOI: 10.1371/journal.pone.0189073

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